Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make their predictions remains a significant challenge, but explainability tools help provide insights into what models have learned when corresponding histologic features are poorly defined. Here, we present a method for improving explainability of DNN models using synthetic histology generated by a conditional generative adversarial network (cGAN). We show that cGANs generate high-quality synthetic histology images that can be leveraged for explaining DNN models trained to classify molecularly-subtyped tumors, exposing histologic features associated with molecular state. Fine-tuning synthetic histology through class and layer blending illustrates nuanced morphologic differences between tumor subtypes. Finally, we demonstrate the use of synthetic histology for augmenting pathologist-in-training education, showing that these intuitive visualizations can reinforce and improve understanding of histologic manifestations of tumor biology.

弱监督的对象本地化（WSOL）旨在学习仅使用图像级类别标签编码对象位置的表示形式。但是，许多物体可以在不同水平的粒度标记。它是动物，鸟还是大角的猫头鹰？我们应该使用哪些图像级标签？在本文中，我们研究了标签粒度在WSOL中的作用。为了促进这项调查，我们引入了Inatloc500，这是一个新的用于WSOL的大规模细粒基准数据集。令人惊讶的是，我们发现选择正确的训练标签粒度比选择最佳的WSOL算法提供了更大的性能。我们还表明，更改标签粒度可以显着提高数据效率。

我们展示了一个下一代神经网络架构，马赛克，用于移动设备上的高效和准确的语义图像分割。MOSAIC是通过各种移动硬件平台使用常用的神经操作设计，以灵活地部署各种移动平台。利用简单的非对称编码器 - 解码器结构，该解码器结构由有效的多尺度上下文编码器和轻量级混合解码器组成，以从聚合信息中恢复空间细节，Mosaic在平衡准确度和计算成本的同时实现了新的最先进的性能。基于搜索的分类网络，马赛克部署在定制的特征提取骨架顶部，达到目前行业标准MLPerf型号和最先进的架构，达到5％的绝对精度增益。

当通过相机或图片与对象交互时，用户通常具有特定的意图。例如，他们可能想执行视觉搜索。由于大多数对象检测模型依靠图像像素作为其唯一输入，因此不希望的结果并不少见。最常见的是：缺乏对感兴趣的对象的高信心检测，或使用错误的类标签检测。当操作容量受限的移动对象检测器上设置时，问题尤其严重。在本文中，我们调查了调节移动检测器的技术，以明确说明用户意图，以简单查询的嵌入表示。与标准探测器相比，查询调制的检测器在检测给定用户查询的对象时表现出卓越的性能。得益于从标准对象检测注释中合成的大规模训练数据，查询调制的检测器也表现出色的转介表达识别系统。还可以对查询调制的检测器进行培训，以同时解决本地化用户查询和标准检测的求解，即使在规范可可任务上甚至超过了标准移动检测器。

We present the next generation of MobileNets based on a combination of complementary search techniques as well as a novel architecture design. MobileNetV3 is tuned to mobile phone CPUs through a combination of hardwareaware network architecture search (NAS) complemented by the NetAdapt algorithm and then subsequently improved through novel architecture advances. This paper starts the exploration of how automated search algorithms and network design can work together to harness complementary approaches improving the overall state of the art. Through this process we create two new MobileNet models for release: MobileNetV3-Large and MobileNetV3-Small which are targeted for high and low resource use cases. These models are then adapted and applied to the tasks of object detection and semantic segmentation. For the task of semantic segmentation (or any dense pixel prediction), we propose a new efficient segmentation decoder Lite Reduced Atrous Spatial Pyramid Pooling (LR-ASPP). We achieve new state of the art results for mobile classification, detection and segmentation. MobileNetV3-Large is 3.2% more accurate on ImageNet classification while reducing latency by 20% compared to MobileNetV2. MobileNetV3-Small is 6.6% more accurate compared to a MobileNetV2 model with comparable latency. MobileNetV3-Large detection is over 25% faster at roughly the same accuracy as Mo-bileNetV2 on COCO detection. MobileNetV3-Large LR-ASPP is 34% faster than MobileNetV2 R-ASPP at similar accuracy for Cityscapes segmentation.

Designing convolutional neural networks (CNN) for mobile devices is challenging because mobile models need to be small and fast, yet still accurate. Although significant efforts have been dedicated to design and improve mobile CNNs on all dimensions, it is very difficult to manually balance these trade-offs when there are so many architectural possibilities to consider. In this paper, we propose an automated mobile neural architecture search (MNAS) approach, which explicitly incorporate model latency into the main objective so that the search can identify a model that achieves a good trade-off between accuracy and latency. Unlike previous work, where latency is considered via another, often inaccurate proxy (e.g., FLOPS), our approach directly measures real-world inference latency by executing the model on mobile phones. To further strike the right balance between flexibility and search space size, we propose a novel factorized hierarchical search space that encourages layer diversity throughout the network. Experimental results show that our approach consistently outperforms state-of-the-art mobile CNN models across multiple vision tasks. On the ImageNet classification task, our MnasNet achieves 75.2% top-1 accuracy with 78ms latency on a Pixel phone, which is 1.8× faster than MobileNetV2 [29] with 0.5% higher accuracy and 2.3× faster than NASNet [36] with 1.2% higher accuracy. Our MnasNet also achieves better mAP quality than MobileNets for COCO object detection. Code is at https://github.com/tensorflow/tpu/ tree/master/models/official/mnasnet.

Transferring the knowledge learned from large scale datasets (e.g., ImageNet) via fine-tuning offers an effective solution for domain-specific fine-grained visual categorization (FGVC) tasks (e.g., recognizing bird species or car make & model). In such scenarios, data annotation often calls for specialized domain knowledge and thus is difficult to scale. In this work, we first tackle a problem in large scale FGVC. Our method won first place in iNaturalist 2017 large scale species classification challenge. Central to the success of our approach is a training scheme that uses higher image resolution and deals with the long-tailed distribution of training data. Next, we study transfer learning via fine-tuning from large scale datasets to small scale, domainspecific FGVC datasets. We propose a measure to estimate domain similarity via Earth Mover's Distance and demonstrate that transfer learning benefits from pre-training on a source domain that is similar to the target domain by this measure. Our proposed transfer learning outperforms Im-ageNet pre-training and obtains state-of-the-art results on multiple commonly used FGVC datasets.

In this paper we describe a new mobile architecture, MobileNetV2, that improves the state of the art performance of mobile models on multiple tasks and benchmarks as well as across a spectrum of different model sizes. We also describe efficient ways of applying these mobile models to object detection in a novel framework we call SSDLite. Additionally, we demonstrate how to build mobile semantic segmentation models through a reduced form of DeepLabv3 which we call Mobile DeepLabv3.is based on an inverted residual structure where the shortcut connections are between the thin bottleneck layers. The intermediate expansion layer uses lightweight depthwise convolutions to filter features as a source of non-linearity. Additionally, we find that it is important to remove non-linearities in the narrow layers in order to maintain representational power. We demonstrate that this improves performance and provide an intuition that led to this design.Finally, our approach allows decoupling of the input/output domains from the expressiveness of the transformation, which provides a convenient framework for further analysis. We measure our performance on ImageNet [1] classification, COCO object detection [2], VOC image segmentation [3]. We evaluate the trade-offs between accuracy, and number of operations measured by multiply-adds (MAdd), as well as actual latency, and the number of parameters.

The recent increase in public and academic interest in preserving biodiversity has led to the growth of the field of conservation technology. This field involves designing and constructing tools that utilize technology to aid in the conservation of wildlife. In this article, we will use case studies to demonstrate the importance of designing conservation tools with human-wildlife interaction in mind and provide a framework for creating successful tools. These case studies include a range of complexities, from simple cat collars to machine learning and game theory methodologies. Our goal is to introduce and inform current and future researchers in the field of conservation technology and provide references for educating the next generation of conservation technologists. Conservation technology not only has the potential to benefit biodiversity but also has broader impacts on fields such as sustainability and environmental protection. By using innovative technologies to address conservation challenges, we can find more effective and efficient solutions to protect and preserve our planet's resources.

A Digital Twin (DT) is a simulation of a physical system that provides information to make decisions that add economic, social or commercial value. The behaviour of a physical system changes over time, a DT must therefore be continually updated with data from the physical systems to reflect its changing behaviour. For resource-constrained systems, updating a DT is non-trivial because of challenges such as on-board learning and the off-board data transfer. This paper presents a framework for updating data-driven DTs of resource-constrained systems geared towards system health monitoring. The proposed solution consists of: (1) an on-board system running a light-weight DT allowing the prioritisation and parsimonious transfer of data generated by the physical system; and (2) off-board robust updating of the DT and detection of anomalous behaviours. Two case studies are considered using a production gas turbine engine system to demonstrate the digital representation accuracy for real-world, time-varying physical systems.